RARE ASSIST — HPP Access Navigator

Navigating the HPP
Treatment Access Journey

RARE ASSIST is a personalized concierge service supporting physicians in Individual Patient Funded (IPF) markets to initiate HPP therapy in less than 3 months from confirmed diagnosis.

⚠️ This is an unbranded educational resource for healthcare professionals only. All content is for informational purposes and does not constitute medical advice.

Select your country to get started

Where are you in the HPP journey?
Select the stage that best describes your current situation to get tailored guidance and support.

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DIAGNOSIS

Confirming HPP with proper testing and clinical criteria

Start Here →

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APPLICATION

Preparing and submitting the IPF funding request

Start Here →

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APPEAL

Responding to a denial and resubmitting your case

Start Here →

One-on-One Support

Need Personalized Guidance?

Connect with a RARE ASSIST Navigator for end-to-end, compliant support through the access process.

Documentation review and preparation
Application submission coordination
Appeals strategy and support
Stakeholder communication

HPP Treatment Access Pathway —

Step-by-step overview of the Individual Patient Funding (IPF) process from diagnosis to treatment initiation. Click any step for guidance, or at any stage.

Diagnosis & Testing

Confirm HPP: low serum ALP, ALPL genetic testing, biomarkers (PLP, PEA), clinical assessment

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Gather Documentation

Medical history, lab results, specialist letters, functional assessments, quality of life data

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Prepare Application

Letter of medical necessity, patient consent forms, supporting clinical evidence

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Submit to Authority

Submit IPF application to the relevant health authority in your country

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Review Process

Authority reviews the application — timeline varies by country. Navigator monitors status.

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✅ APPROVED

Proceed to therapy initiation

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6
Treatment Initiation
Patient onboarding, first infusion, monitoring plan
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7
Reauthorization
Annual renewal where applicable in your country
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❌ If Denied

Review denial reason

Prepare appeal with additional evidence

Resubmit to authority

Target timeline from diagnosis to treatment < 3 months with RARE ASSIST concierge support

Navigating the HPP
Treatment Access Journey

Welcome to RARE ASSIST —

Need Personalized Guidance?

Request RARE ASSIST Navigator Support

Your Request Has Been Received

Navigating the HPPTreatment Access Journey

Welcome to RARE ASSIST —

Need Personalized Guidance?

Request RARE ASSIST Navigator Support

Your Request Has Been Received

Navigating the HPP
Treatment Access Journey